As with any event of this nature, Ayaan Hirsi Ali should always be considered seriously. Key quote:
In Islam, it is a grave sin to visually depict or in any way slander the Prophet Muhammad. Muslims are free to believe this, but why should such a prohibition be forced on nonbelievers? In the U.S., Mormons didn’t seek to impose the death penalty on those who wrote and produced “The Book of Mormon,” a satirical Broadway sendup of their faith. Islam, with 1,400 years of history and some 1.6 billion adherents, should be able to withstand a few cartoons by a French satirical magazine. But of course deadly responses to cartoons depicting Muhammad are nothing new in the age of jihad.
She has a book on the need for a Muslim reformation coming in April. It should be on everyone’s must read list.